20 research outputs found

    Hydromagnetic Flow with Thermal Radiation

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    The Feasibility of Multidimensional CFD Applied to Calandria System in the Moderator of CANDU-6 PHWR Using Commercial and Open-Source Codes

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    The moderator system of CANDU, a prototype of PHWR (pressurized heavy-water reactor), has been modeled in multidimension for the computation based on CFD (computational fluid dynamics) technique. Three CFD codes are tested in modeled hydrothermal systems of heavy-water reactors. Commercial codes, COMSOL Multiphysics and ANSYS-CFX with OpenFOAM, an open-source code, are introduced for the various simplified and practical problems. All the implemented computational codes are tested for a benchmark problem of STERN laboratory experiment with a precise modeling of tubes, compared with each other as well as the measured data and a porous model based on the experimental correlation of pressure drop. Also the effect of turbulence model is discussed for these low Reynolds number flows. As a result, they are shown to be successful for the analysis of three-dimensional numerical models related to the calandria system of CANDU reactors

    Genome-Wide Analyses of Nkx2-1 Binding to Transcriptional Target Genes Uncover Novel Regulatory Patterns Conserved in Lung Development and Tumors

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    The homeodomain transcription factor Nkx2-1 is essential for normal lung development and homeostasis. In lung tumors, it is considered a lineage survival oncogene and prognostic factor depending on its expression levels. The target genes directly bound by Nkx2-1, that could be the primary effectors of its functions in the different cellular contexts where it is expressed, are mostly unknown. In embryonic day 11.5 (E11.5) mouse lung, epithelial cells expressing Nkx2-1 are predominantly expanding, and in E19.5 prenatal lungs, Nkx2-1-expressing cells are predominantly differentiating in preparation for birth. To evaluate Nkx2-1 regulated networks in these two cell contexts, we analyzed genome-wide binding of Nkx2-1 to DNA regulatory regions by chromatin immunoprecipitation followed by tiling array analysis, and intersected these data to expression data sets. We further determined expression patterns of Nkx2-1 developmental target genes in human lung tumors and correlated their expression levels to that of endogenous NKX2-1. In these studies we uncovered differential Nkx2-1 regulated networks in early and late lung development, and a direct function of Nkx2-1 in regulation of the cell cycle by controlling the expression of proliferation-related genes. New targets, validated in Nkx2-1 shRNA transduced cell lines, include E2f3, Cyclin B1, Cyclin B2, and c-Met. Expression levels of Nkx2-1 direct target genes identified in mouse development significantly correlate or anti-correlate to the levels of endogenous NKX2-1 in a dosage-dependent manner in multiple human lung tumor expression data sets, supporting alternative roles for Nkx2-1 as a transcriptional activator or repressor, and direct regulator of cell cycle progression in development and tumors

    Numerical Analysis on the Calandria Tubes in the Moderator of a Heavy Water Reactor Using OpenFOAM and Other Codes

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    CANDU, a prototype of heavy water reactor is modeled for the moderator system with porous media buoyancy-effect heat-transfer turbulence model. OpenFOAM, a set of C++ classes and libraries developed under the object-oriented concept, is selected as the tool of numerical analysis. The result from this computational code is compared with experiments and other commercial code data through ANSYS-CFX and COMSOL Multi-physics. The three-dimensional code concerning buoyancy force, turbulence, and heat transfer is tested and shown to be successful for the analysis of thermo-hydraulic system of heavy water reactors

    Low-frequency modes in the fluid-structure interaction of a U-tube model for the steam generator in a PWR

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    In the SG (steam generator) of PWR (pressurized water reactor) for a nuclear plant, hundreds of U-shaped tubes are used for the heat exchanger system. They interact with primary pressurized cooling water flow, generating flow-induced vibration in the secondary flow region. A simplified U-tube model is proposed in this study to apply for experiment and its counterpart computation. Using the commercial code, ANSYS-CFX, we first verified the Moody chart, comparing the straight pipe theory with the results derived from CFD (computational fluid dynamics) analysis. Considering the virtual mass of fluid, we computed the major modes with the low natural frequencies through the comparison with impact hammer test, and then investigated the effect of pump flow in the frequency domain using FFT (fast Fourier transform) analysis of the experimental data. Using two-way fluid-structure interaction module in the CFD code, we studied the influence on mean flow rate to generate the displacement data. A feasible CFD method has been setup in this research that could be applied potentially in the field of nuclear thermal-hydraulics. Keywords: Fluid-structure interaction, U-tube, Steam generator, CFD, Flow-induced vibratio

    Parametric Study on the Mixing Enhancement of Parallel Supersonic-subsonic Wakes Using Wall Cavities

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    A series of computational studies on the enhancement of parallel supersonic-subsonic mixing wakes, where M1 1⁄4 1.78 and M2 1⁄4 0.30 at baseline, is conducted and compared with available experimental data. The mixing problem of this parallel flow is characterized by the interaction of complex turbulent shear flow with acoustic waves emitted from a wall-mounted cavity. The first aim of the present work is to show a direct comparison between numerical predictions and equivalent experimental data for the baseline case. Hence we make a comparison of eight independent turbulence models, which were selected from the most widely using turbulence models in use in the engineering field, consisting of six eddy–viscosity models and two Reynolds stress models. The Pitot pressure distribution data are in good agreement between computation and experiment, and the results show that Menters SST model gives the best performance. Further, we investigate the effects of primary parameters such as the length-to-depth (L/D) ratio of the cavity, the position of the cavity, and the arrangement of the cavity at the given flow condition. Consequently, this methodology can contribute to finding an optimal guideline for the idea of mixing enhancement in the free turbulent wake using the acoustic wave produced by wall cavities

    A Simplified Numerical Model for the Prediction of Wake Interaction in Multiple Wind Turbines

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    In the design of wind energy farms, the loss of power should be seriously considered for the second wind turbine located inside the wake region of the first one. The rotation of the first wind-front rotor generates a high-vorticity wake with turbulence, and a suitable model is required in computational fluid dynamics (CFD) to predict the deficit of energy of the second turbine for the given configuration. A simplified numerical model based on the classical momentum theory is proposed in this study for multiple wind turbines, which is proposed with a couple of tuning parameters applied to Reynolds-averaged Navier-Stokes (RANS) analysis, resulting in a remarkable reduction of computational load compared with advanced methods, such as large eddy simulation (LES) where two parameters reflect on axial and rotational wake motion, simply tuned with the wind-tunnel test and its corresponding LES result. As a lumped parameter for the figure of merit, we regard the normalized efficiency on the kinetic power output of computational domain, which should be directed to maximize for the optimization of wind farms. The parameter surface is plotted in a dimensionless form versus intervals between turbines, and a simple correlation is obtained for a given hub height of 70% diameter and a fixed rotational speed tuned from the experimental data in a wide range

    Unsteady Simulation of a Full-Scale CANDU-6 Moderator with OpenFOAM

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    Three-dimensional moderator flow in the calandria tank of CANDU-6 pressurized heavy water reactor (PHWR) is computed with Open Field Operation and Manipulation (OpenFOAM), an open-source computational fluid dynamics (CFD) code. In this study, numerical analysis is performed on the real geometry model including 380 fuel rods in the calandria tank with the heat-source distribution to remove uncertainty of the previous analysis models simplified by the porous media approach. Realizable k-ε turbulence model is applied, and the buoyancy due to temperature variation is considered by Boussinesq approximation for the incompressible single-phase Navier-Stokes equations. The calculation results show that the flow is highly unsteady in the moderator. The computational flow visualization shows a circulation of flow driven by buoyancy and asymmetric oscillation at the pseudo-steady state. There is no region where the local temperature rises continuously due to slow circulating flow and its convection heat transfer
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